Field of Study, Definition and Classification
Definition: What is Parasitology?
Generally speaking, parasitology is the branch of microbiology that is concerned with the study of parasites. In the process, it gives focus to various characteristics of the parasite (morphology, life-cycle, ecology, taxonomy, etc), the type of host they infect/affect and the relationship between the two.
In parasitology, parasites have traditionally been restricted to three main groups that include protozoa, helminths, and arthropods. However, they are also described based on where they are located on the host: Ectoparasites (those that live on the host- skin, etc) and endoparasites (those that live inside the body of the host).
As a sub-discipline that studies a wide variety of organisms and relationship with their hosts, parasitology also encompasses some elements of such fields as entomology, helminthology, and epidemiology among others.
* For the most part, parasites (living organisms) are permanently associated with their respective hosts (or need a host for a given stage of their lives). For this reason, such organisms like tsetse flies that briefly feed on given animals are not necessarily regarded as parasites in medical parasitology.
Examples of parasites include:
- T. gondii
- P. carinii
- P. falciparum
Parasites of medical significance are divided into two main categories that include single-celled parasites (protozoa) and multicellular metazoa (helminths and arthropods).
Protozoa parasites include malaria parasites (Plasmodium species) ciliates (e.g. B. coli) and flagellates (e.g. Leishmania), and amoeba (e.g. E. histolytica) among others. These are single-celled organisms that generally live inside the body of the host. For instance, whereas E. histolytica can be found in the gut, malaria parasites like P. falciparum invade red cells inside the body.
In the body, classification of protozoa parasites are based on the mode of movement:
- Mastigophora - Use flagella for movement
- Sporozoa - Are non- motile in the body
- Sarcodina - Use amoeboid movement
- Ciliophora - Use cilia for movement
As they obtain nutrition from the host (depending on where they are located) parasites are able to multiply and increase in number. This ensures their survival as they can be transmitted from one host to another.
During unfavorable conditions, they are also able to transform from the active trophozoite stage to inactive cysts that survive unfavorable conditions.
Unlike protozoa, helminths are multicellular parasites that tend to be bilaterally symmetrical. They include members of cestode (e.g tapeworm), trematode (e.g flukes) and nematodes such as roundworms.
Like protozoa, however, helminths are endoparasites that are generally found in the gastrointestinal tract. Using suckers or hooks (found in cestodes and trematodes), these organisms are able to remain attached to the walls of the gastrointestinal tract and continue absorbing nutrients. This not only deprives the host of sufficient nutrients, but also tends to cause injury to the gastrointestinal walls.
Compared to protozoa parasites that tend to proliferate in the host, helminths mostly grow and mature. Offspring are then voided from the host and may through several life stages before infecting a new host. For instance, some eggs may develop into the larval stage in animal hosts before being ingested in their larval stage in a human host.
In human hosts, larval and adult forms of these parasites may cause:
- Lesions in the gastrointestinal tract
- Edema as a result of fluid accumulation - This is often related to obstruction
Like helminths, arthropods are multicellular organisms that are bilaterally symmetrical. However, unlike helminths, arthropods have jointed appendages used for movement and attachment as well as a hard exoskeleton that protects the internal organs of the parasites.
For arthropods, these are important characteristics that allow these parasites to survive as ectoparasites. Unlike both the protozoa parasites and helminths, arthropods are ectoparasites which means that they are found attached to the skin of the host.
Examples of arthropods include lice, fleas, and ticks. Here, arthropods affect the host by sucking their blood as well as by acting as transmitters/vectors. For instance, lice transmit Rickettsia bacteria which causes Trench fever in human beings.
* Such animals as mosquito (female Anopheles mosquito) that depend on human blood as a source of nutrients are not necessarily included in this group given that they feed on the host momentarily.
Apart from classification based on the location of the parasite (ecto and endoparasites) the different types of parasites in parasitology have also been classified based on other relationships between the parasite and the host.
· Obligate parasite - Obligate parasites are fully dependent on the host for a specific stage of their life-cycle or the entire length of their lives. Plasmodium species are good examples of obligate parasites. Once they enter the body, through a mosquito bite, they invade red cells where they obtain nutrients. Here, Plasmodium species are entirely dependent on the host for their survival.
· Facultative parasite - Unlike obligate parasites, facultative parasites are not entirely dependent on the host for survival. As such, they may exhibit parasitic and non-parasitic characteristics by adapting to different conditions. A good example of facultative parasites is the Naegleria fowler. In freshwater, such organisms as bacteria are good sources of food. However, once they get in the body, they cause brain infections (amoebic meningoencephalitis) which can cause death within 5 days.
· Accidental parasites - Also known as incidental parasites, accidental parasites are those that attack or establish themselves in unusual hosts (hosts that they do not normally parasitize). Here, the host is referred to as an unnatural host. In this case, the parasite infects the host and is able to survive and continue growing as it would in the natural host. Rat tapeworms (Hymenolepis diminuta) are good examples of accidental parasites. Although they must affect rats, these parasites have been shown to affect human beings.
· Erratic parasites - Erratic parasites are parasites that invade body organs that they do not normally invade. E. histolytica is a good example of erratic parasites. Typically, this anaerobic parasite is found in the gastrointestinal tract where they cause amoebiasis (bloody diarrhea). However, the parasite has been shown to wander and invade such organs as the liver and lungs in human beings.
See also other fields of study:
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Alan Gunn and Sarah, J. Pitt. (2012). Parasitology: An Integrated Approach.
Dawit Assafa, et al. (2004). Medical Parasitology. LECTURE NOTES.
Manar Mahmoud El-Tonsy. (2012). Introduction To Medical Parasitology. ResearchGate.